Exploring the complex relationship between gut microbiota and risk of colorectal neoplasia using bidirectional Mendelian Randomization analysis.
Wanxin LiXuan ZhouQiqiang HeLijuan WangLili YuJing SunTherese HeskethQian XiaoZhong-Xiao WanJu-Sheng ZhengCai-Xia ZhangSusanna C LarssonSusan M FarringtonPhilip J LawRichard S HoulstonIan P M TomlinsonKe-Feng DingMalcolm G DunlopEvropi TheodoratouXue LiPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)
This study highlights the need of future complementary studies to explore causal mechanisms linking both host genetic variation with gut microbiome and CRC susceptibility.