Causal effect of adiposity on the risk of 19 gastrointestinal diseases: a Mendelian randomization study.

Min Seo KimMinku SongSoyeon KimBeomsu KimWonseok KangJong Yeob KimWoojae MyungInhyeok LeeRon DoAmit V KheraHong-Hee Won

Published in: Obesity (Silver Spring, Md.) (2023)

High genetically predicted adiposity was causally associated with an increased risk of GI abnormalities, particularly of hepatobiliary organs (liver, biliary tract, and gallbladder) that are functionally related to fat metabolism.

Keyphrases

insulin resistance
adipose tissue
weight gain
type diabetes
body mass index
metabolic syndrome
physical activity
weight loss
skeletal muscle