Dorsal Root Ganglion Stimulation in Experimental Painful Diabetic Polyneuropathy: Delayed Wash-Out of Pain Relief After Low-Frequency (1Hz) Stimulation.

Eva Koetsier Glenn FrankenJacques DebetsSander M J van KuijkBengt LinderothElbert A JoostenPaolo Maino

Published in: Neuromodulation : journal of the International Neuromodulation Society (2019)

These results show that DRGS is equally effective when applied at low-, mid-, and high-frequency in an animal model of PDPN. However, low-frequency-(1 Hz)-DRGS resulted in a delayed wash-out effect, which suggests that this is the most optimal frequency for pain therapy in PDPN as compared to mid- and high-frequency.

Keyphrases

high frequency
neuropathic pain
transcranial magnetic stimulation
chronic pain
spinal cord
pain management
spinal cord injury
type diabetes
stem cells
mesenchymal stem cells
optical coherence tomography