A Randomized Controlled Trial of R-Form Verapamil Added to Ongoing Metformin Therapy in Patients with Type 2 Diabetes.
Chih-Yuan WangKuo-Chin HuangChia-Wen LuChih-Hsun ChuChien-Ning HuangHarn-Shen ChenI-Te LeeJung-Fu ChenChing-Chu ChenChung-Sen ChenChang-Hsun HsiehKai-Jen TienHung-Yu ChienYu-Yao HuangJui-Pao HsuGuang-Tzuu ShaneAi-Ching ChangYen-Chieh WuWayne Huey Herng SheuPublished in: The Journal of clinical endocrinology and metabolism (2022)
Addition of R-Vera twice daily to ongoing metformin therapy significantly improved glycemic control in T2DM patients. The favorable efficacy and safety profile of R-Vera 300 mg/day can be considered as the appropriate dose for clinical practice.