Radiation dose response of neurologic symptoms during conformal radiotherapy for diffuse intrinsic pontine glioma.

Christopher L TinkleKristen CampbellYuanyuan HanYimei LiBrandon BianskiAlberto BroniscerRaja B KhanThomas E Merchant

Published in: Journal of neuro-oncology (2020)

Low cumulative RT doses resulted in neurologic improvement in most patients with DIPG. The volume of brainstem spared by tumor influenced time to symptomatic improvement. Neurologic improvement during RT was associated with superior survival.

Keyphrases

early stage
radiation therapy
neuropathic pain
radiation induced
depressive symptoms