Exhaled nitric oxide is only an asthma-relevant biomarker among children with allergic sensitization.
Rikke Bjersand SundeJonathan ThorsenFrederikke SkovLaura HesselbergJulie Nyholm KyvsgaardNilofar V FølsgaardAnn-Marie Malby SchoosJessica Lasky-SuKlaus BønnelykkeBo Lund ChawesPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2023)
Fraction of exhaled nitric oxide is elevated through childhood in children with asthma and is correlated with asthma-associated traits depending on the presence of aeroallergen sensitization. These findings indicate that FeNO is only a valid asthma biomarker in children with concurrent aeroallergen sensitization, which is important for guideline recommendations on the clinical use of FeNO.