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Combined meta-analysis of preclinical cell therapy studies shows overlapping effect modifiers for multiple diseases.

Peter-Paul ZwetslootAna Antonic-BakerCoen D A StehouwerKimberley Elaine WeverChris SenaSanne Jansen Of LorkeersSteven ChamuleauJoost SluijterDavid W Howells
Published in: BMJ open science (2021)
Preclinical cell therapy studies are affected by multiple variables, including species, immunosuppression, dose and treatment timing. These data are important when designing preclinical studies before commencing clinical trials.
Keyphrases
  • cell therapy
  • case control
  • stem cells
  • mesenchymal stem cells
  • clinical trial
  • systematic review
  • meta analyses
  • machine learning
  • open label
  • combination therapy
  • phase ii
  • smoking cessation