Systematic follow-up examinations of patients cured of testicular cancer first gained attention by caregivers in the 1980s only after the management of the disease had significantly been improved by the introduction of cisplatin-based chemotherapy and almost synchronously, by the implementation of computerized tomography (CT) and serum tumor markers. Follow-up involves three aims: early diagnosis of recurrence, detection of treatment-related toxicity, and detection of secondary diseases. As the clinical presentation of testicular cancer is very heterogeneous, there is no uniform follow-up for the disease. Instead, risk-adapted follow-up schedules are required. Since the release of the German AWMF S3 guideline for the management of testicular cancer in 2019, high level evidence has accumulated for the noninferiority of magnetic resonance imaging (MRI) to CT with regard to abdominal imaging. Therefore, it is appropriate to modify the recommendations for follow-up given in the 2019 issue of the S3 guidelines. The modifications recommended herein relate to three issues: (1) Only three risk groups (instead of formerly four) are identified, i.e., seminoma (all stages); nonseminoma clinical stage 1b (i.e., pT2, with lymphovascular invasion) on surveillance; nonseminoma all other stages. All patients cured from poor risk disease or from relapses require individual follow-up schedules not included in the recommendations tabulated herein. (2) CT and abdominal sonography are replaced by MRI. (3) Chest X‑ray imaging during follow-up of seminoma patients is no longer recommended.
Keyphrases
- germ cell
- magnetic resonance imaging
- contrast enhanced
- end stage renal disease
- ejection fraction
- computed tomography
- newly diagnosed
- high resolution
- prognostic factors
- healthcare
- squamous cell carcinoma
- papillary thyroid
- dual energy
- peritoneal dialysis
- image quality
- palliative care
- public health
- radiation therapy
- working memory
- rectal cancer
- lymph node metastasis
- pet ct
- label free
- young adults
- loop mediated isothermal amplification
- endometrial cancer
- smoking cessation
- quantum dots
- quality improvement