Population Pharmacokinetic modeling of fibrinogen in patients with congenital or acquired -chronic or acute- hypofibrinogenemia.

Helena ColomAnnabel BlasiBruno MontoroAngel Guillermo ArévaloJosep Maria CendrósAntoni Sabaté

Published in: British journal of clinical pharmacology (2023)

This model will be key as a support tool for dose calculation to achieve specified target fibrinogen concentrations, in each of the studied populations.

Keyphrases

liver failure
drug induced
respiratory failure
aortic dissection
hepatitis b virus
genetic diversity
mechanical ventilation