Login / Signup

Development of [ 225 Ac]Ac-DOTA-C595 as radioimmunotherapy of pancreatic cancer: in vitro evaluation, dosimetric assessment and detector calibration.

Ashleigh HullWilliam HsiehArtem BorysenkoWilliam TieuDylan BartholomeuszEva Bezak
Published in: EJNMMI radiopharmacy and chemistry (2023)
Ac]Ac-DOTA-C595 was shown to target and induce a therapeutic effect in MUC1-CE expressing PDAC cells.
Keyphrases
  • pet ct
  • pet imaging
  • induced apoptosis
  • radiation therapy
  • cell cycle arrest
  • cell death
  • cell proliferation
  • signaling pathway
  • low cost
  • wild type
  • clinical evaluation