Multi-omics links IL-6 trans-signalling with neutrophil extracellular trap formation and Haemophilus infection in COPD.

Sofia WinslowLina OdqvistSarah DiverRebecca RiiseSuado AbdillahiCecilia WingrenHelena LindmarkAnnika WellnerSofia LundinLinda YrlidElisabeth AxRatko DjukanovicSriram SridharAndrew HighamDave SinghThomas SouthworthChristopher E BrightlingHenric K OlssonZala Jevnikar

Published in: The European respiratory journal (2021)

IL-6TS pathway activation due to chronic colonisation with Haemophilus may be an important disease driver in a subset of COPD patients.

Keyphrases

chronic obstructive pulmonary disease
end stage renal disease
ejection fraction
lung function
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes