Timing of dialysis initiation to reduce mortality and cardiovascular events in advanced chronic kidney disease: nationwide cohort study.
Edouard L FuMarie EvansJuan-Jesus CarreroHein PutterCatherine M ClaseFergus J CaskeyMaciej SzymczakClaudia TorinoNicholas C ChesnayeKitty J JagerChristoph WannerFriedo W DekkerMerel van DiepenPublished in: BMJ (Clinical research ed.) (2021)
Very early initiation of dialysis was associated with a modest reduction in mortality and cardiovascular events. For most patients, such a reduction may not outweigh the burden of a substantially longer period spent on dialysis.