Association of leptin and leptin receptor polymorphisms with coronary artery disease in a North Chinese Han population.

Haidong WangChao WangWenxiu HanChunmei GengDan ChenBin WuJun ZhangChangshui WangHaidong Wang

Published in: Revista da Sociedade Brasileira de Medicina Tropical (2020)

The current study detected a significant association between genetic variations at LEP rs7799039 and rs2167270 and the risk of CAD in a north Chinese population, and revealed that LEP rs2167270 and rs7799039 gene polymorphisms might act as predisposing factors for CAD.

Keyphrases

coronary artery disease
percutaneous coronary intervention
cardiovascular events
coronary artery bypass grafting
tertiary care
genome wide
single cell
gene expression
copy number
acute coronary syndrome
left ventricular
aortic valve