Glutathione metabolism in type 2 diabetes and its relationship with microvascular complications and glycemia.

Fallon K LutchmansinghJean W HsuFranklyn I BennettAsha V BadalooNorma McFarlane-AndersonGeorgiana M Gordon-StrachanRosemarie A Wright-PascoeFarook JahoorMichael S Boyne

Published in: PloS one (2018)

Compared to non-diabetic controls, patients with T2DM have glutathione deficiency, especially if they have microvascular complications. This is probably due to reduced synthesis and increased irreversible utilization by non-glycemic mechanisms.

Keyphrases

type diabetes
glycemic control
risk factors
cardiovascular disease
insulin resistance
wound healing
replacement therapy
metabolic syndrome