A Whole-Grain Diet Reduces Cardiovascular Risk Factors in Overweight and Obese Adults: A Randomized Controlled Trial.
John P KirwanSteven K MalinAmanda R ScelsiEmily L KullmanSankar D NavaneethanMangesh R PagadalaJacob M HausJulianne FilionJean-Philippe GodinSunil KochharAlastair B RossPublished in: The Journal of nutrition (2016)
The improvement in diastolic blood pressure was >3-fold greater in overweight and obese adults when they consumed a whole-grain compared with a refined-grain diet. Because diastolic blood pressure predicts mortality in adults aged <50 y, increased whole-grain intake may provide a functional approach to control hypertension. This may benefit patients at risk of vascular-related morbidity and mortality. This trial was registered at clinicaltrials.gov as NCT01411540.
Keyphrases
- blood pressure
- cardiovascular risk factors
- hypertensive patients
- heart rate
- weight loss
- left ventricular
- physical activity
- cardiovascular disease
- clinical trial
- heart failure
- cardiovascular events
- ejection fraction
- coronary artery disease
- body mass index
- phase iii
- insulin resistance
- adipose tissue
- arterial hypertension