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TP53 -specific mutations serve as a potential biomarker for homologous recombination deficiency in breast cancer: a clinical next-generation sequencing study.

Yongsheng HuangShuwei RenLinxiaoxiao DingYuanling JiangJiahuan LuoJinghua HuangXinke YinJianli ZhaoSha FuJianwei Liao
Published in: Precision clinical medicine (2024)
pathogenic mutations could serve as a potential biomarker for poly-ADP-ribose polymerase (PARP) inhibitors in breast cancer patients .
Keyphrases
  • dna repair
  • dna damage
  • copy number
  • oxidative stress
  • gene expression
  • replacement therapy
  • smoking cessation
  • breast cancer risk