The Association Between Drug Burden Index (DBI) and Health-Related Outcomes: A Longitudinal Study of the 'Oldest Old' (LiLACS NZ).

Karen CardwellNgaire KerseCristín RyanRuth TehSimon A MoyesOliver MenziesAnna RollestonJoanna BroadCarmel M Hughes

Published in: Drugs & aging (2020)

Using data from LiLACS NZ, a higher DBI was significantly associated with a greater risk of mortality (in Māori and non-Māori) and impaired cognitive function (in non-Māori). This highlights the importance of employing strategies to manage the prescribing of medications with a DBI > 0 in older adults.

Keyphrases

primary care
risk factors
physical activity
adverse drug
electronic health record
cardiovascular events
big data
type diabetes
machine learning
coronary artery disease
drug induced
metabolic syndrome
glycemic control