Identification of Active Bronchioalveolar Stem Cells as the Cell of Origin in Lung Adenocarcinoma.

Huijing YinBo JingDongliang XuWenzheng GuoBeibei SunJie ZhangYueling LiaoHongyong SongTong WangShuli LiuYueling LiaoMin HuKaimi LiSiwei ZhangHongjia ZhangJianhua XuXue LiJing DuYadi WuYing-Li WuQi WangFeng YaoYueh Eugene ChinBinhua P ZhouJiong Deng

Published in: Cancer research (2022)

Identification of active bronchioalveolar stem cells as lung adenocarcinoma cells of origin provides insights into mechanisms of lung tumorigenesis and could facilitate development of effective strategies for cancer prevention and therapy. See related commentary by Osborne and Minna, p. 972.

Keyphrases

stem cells
cell therapy
induced apoptosis
papillary thyroid
bioinformatics analysis
single cell
oxidative stress
signaling pathway
cell proliferation