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MitoQ and CoQ10 supplementation mildly suppresses skeletal muscle mitochondrial hydrogen peroxide levels without impacting mitochondrial function in middle-aged men.

Toan PhamCaitlin L MacRaeSophie C BroomeRandall F D'souzaRavi NarangHsiang W WangTrevor A MoriAnthony J R HickeyCameron J MitchellTroy L Merry
Published in: European journal of applied physiology (2020)
Our results suggest that neither MitoQ and CoQ10 supplements impact mitochondrial function, but both can mildly suppress mitochondrial ROS levels in healthy middle-aged men, with some indication that MitoQ may be more effective than CoQ10.
Keyphrases
  • middle aged
  • hydrogen peroxide
  • skeletal muscle
  • oxidative stress
  • nitric oxide
  • insulin resistance
  • dna damage
  • cell death
  • reactive oxygen species
  • metabolic syndrome