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Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy.

Jacqueline AlexanderApril M TeagueJing ChenChristopher E AstonYuet-Kin LeungSteven ChernausekRebecca A SimmonsSara E Pinney
Published in: PloS one (2018)
These findings begin to explain mechanisms responsible for the increased risk for obesity and type 2 diabetes in offspring of mothers with DDP.
Keyphrases
  • type diabetes
  • dna methylation
  • gene expression
  • high fat diet
  • insulin resistance
  • glycemic control
  • genome wide
  • cardiovascular disease
  • weight loss
  • metabolic syndrome
  • adipose tissue
  • high fat diet induced
  • weight gain