TV 3326 for Alzheimer's dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer's-like neuropathology.

Md Sahab UddinMd Tanvir KabirMd Motiar RahmanBijo Mathew Muhammad Ajmal ShahGhulam Md Ashraf

Published in: The Journal of pharmacy and pharmacology (2020)

TV 3326 can avert oxidative-nitrative stress and gliosis. It has also been confirmed that TV 3326 contains neuroprotective and anti-apoptotic properties. Therefore, this distinctive combined inhibition of ChE and MAO along with its neuroprotective property makes TV 3326 a useful drug in the treatment of AD.

Keyphrases

cognitive decline
mild cognitive impairment
cerebral ischemia
cell death
emergency department
pain management
anti inflammatory
brain injury
heat stress