Elevated methemoglobin levels in patients treated with high-dose hydroxocobalamin.
Martinus DyrudJianli NiuLisa KohlerPublished in: Laboratory medicine (2023)
The presence of OHCbl in blood clearly interfered with the oximetry measurements of the hemoglobin component fractions by falsely increasing the levels of MetHb and COHb. Blood levels of MetHb and COHb cannot be reliably determined by the co-oximetry when OHCbl is known or suspected.