Clinical management and innovation in fracture nonunion.
Claudia SiverinoW-J MetsemakersR SutterE Della BellaM MorgensternJ BarcikM ErnstM D'EsteA JoerisM ChittòP SchwarzenbergM StoddartN VanvelkG RichardsE WehrleF WeisemannS ZeiterC ZalavrasP VargaT F MoriartyPublished in: Expert opinion on biological therapy (2024)
The first challenge for future innovations is to refine and to identify new clinical factors for the proper definition, diagnosis and treatment of nonunion. However, integration of in vitro, in vivo, and in silico research will enable a comprehensive understanding of nonunion causes and correlations, leading to the development of more effective treatments.