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FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells.

Weiwei XuYajuan YangYongze YuCanxin WenSimin ZhaoLili CaoShidou ZhaoYingying QinZi-Jiang Chen
Published in: BMC biology (2023)
Our findings suggest that FAAP100 is required for the resolution of TRCs in PGCs to safeguard their genome stability.
Keyphrases
  • induced apoptosis
  • single molecule
  • cell cycle arrest
  • transcription factor
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • genome wide
  • signaling pathway
  • germ cell
  • cell proliferation
  • embryonic stem cells