Synthetic Lethality Beyond BRCA: A Phase I Study of Rucaparib and Irinotecan in Metastatic Solid Tumors With Homologous Recombination-Deficiency Mutations Beyond BRCA1/2.
Erica S TsangMallika S DhawanRomain PacaudScott ThomasJennifer GrabowskyLauren WilchSilpa KaripineniRobin Kate KelleyAndrew H KoEric CollissonJocelyn S ChapmanStefanie UedaEmily K BergslandPamela MunsterPublished in: JCO precision oncology (2024)
-mutated cancers despite progression on previous platinum.