Performance of the Sysmex White Precursor Channel to discover circulating leukemic blast cells.

Jesper SejrupDavid M PedersenJens P PhillipsenJesper Ø NielsenSheila P R KochJulie Smith

Published in: International journal of laboratory hematology (2020)

WPC blast alarm flags are imprecise and inaccurate, especially when blast counts are low. However, the XN20 will alarm samples with other flags so that most samples containing blast cells will be manually reviewed after all. Hence, the presented flag types should not bias the decisions of manual reviewers.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
acute myeloid leukemia
signaling pathway
cell death
oxidative stress
cell proliferation
peripheral blood