Rab35 Is Required for Embryonic Development and Kidney and Ureter Homeostasis through Regulation of Epithelial Cell Junctions.
Kelsey R ClearmanNapassawon TimpratoomDharti PatelAddison B RainsCourtney J HaycraftMandy J CroyleJeremy F ReiterBradley K YoderPublished in: Journal of the American Society of Nephrology : JASN (2024)
Rab35 is essential for mammalian development and the maintenance of kidney and ureter architecture. Loss of Rab35 leads to non-obstructive hydronephrosis, making the Rab35 mutant mouse a novel mammalian model to study mechanisms underlying this disease.
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