Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Household Transmission during the Omicron Era in Massachusetts: A Prospective, Case-Ascertained Study using Genomic Epidemiology.

Jaspreet BangaTaylor Brock-FisherBrittany A PetrosEric Y DaiAriana T LeonelliSabrina T DobbinsKatelyn S MesserAudrey B NathansonAmelia CaponeNancy LittlehaleViola Appiah-DanquahSiang DimGage K MorenoMaura CrowtherKannon A LeeKatherine C DeRuffBronwyn L MacInnisMichael SpringerPardis C SabetiKathryn E Stephenson

Published in: medRxiv : the preprint server for health sciences (2024)

When community transmission of SARS-CoV-2 is high, distinguishing household transmissions from independent introductions is difficult with either epidemiologic or genomic data alone. Here, we conducted daily nasal sampling with genomic sequencing to understand the dynamics of viral transmission within households.

Keyphrases

sars cov
respiratory syndrome coronavirus
copy number
healthcare
coronavirus disease
mental health
physical activity
single cell
electronic health record
risk factors
dna methylation
data analysis