The NLRP3 inflammasome contributes to inflammation-induced morphological and metabolic alterations in skeletal muscle.
Moritz EggelbuschAndi ShiBonnie C BroeksmaMariana Vázquez-CruzMadu N SoaresGerard M J de WitBart EvertsRichard T JaspersRob C I WüstPublished in: Journal of cachexia, sarcopenia and muscle (2022)
LPS-induced activation of the NLRP3 inflammasome in cultured myotubes contributes to morphological and metabolic alterations, likely due to its mitochondrial association.