Replacement of Sedentary Behavior by Various Daily-Life Physical Activities and Structured Exercises: Genetic Risk and Incident Type 2 Diabetes.

Xiang LiTao ZhouHao MaZhaoxia LiangVivian A FonsecaLu Qi

Published in: Diabetes care (2021)

Our study indicates that sedentary behavior time is associated with an increased risk of T2D; replacing sedentary behavior with a short duration (30 min/day) of daily-life physical activities or structured exercise is related to a significant reduction in T2D risk. Furthermore, such association was stronger among those with a lower genetic risk of T2D.

Keyphrases

physical activity
type diabetes
cardiovascular disease
mental health
genome wide
high intensity
copy number
glycemic control
adipose tissue
weight loss