Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cells.

Smrruthi Vaidegi VenugopalSilvia CaggiaDaJhnae Gambrell-SandersShafiq A Khan

Published in: The Prostate (2020)

We suggest that EGF-induced activation of Rac1 causes the activation of mTORC2 via RICTOR. This mechanism plays a critical role in prostate cancer cell migration.

Keyphrases

cell migration
prostate cancer
radical prostatectomy
drug induced