The phosphatase PTPN1/PTP1B is a candidate marker of better chemotherapy response in metastatic high-grade serous carcinoma.

Ben DavidsonAnnika Jøntvedt BockArild HolthDag Andre Nymoen

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2020)

PTPN1 is overexpressed in HGSC compared to MM effusions, and may be a marker of better chemotherapy response in the former. Whether PTPN1 activation is informative of adverse outcome in MM merits further investigation.

Keyphrases

high grade
low grade
locally advanced
squamous cell carcinoma
small cell lung cancer
emergency department
rectal cancer
adverse drug