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Cholesterol depletion induces mesenchymal properties in oral squamous cell carcinoma cell line.

Rebeca Barros do NascimentoPaloma Souza Gonçalves CerqueiraJamerson Carvalho SilvaElisa Kauark FontesElias Almeida Dos SantosJean Nunes Dos SantosFabio Daumas NunesMaria Fernanda Setúbal Destro RodriguesKatiúcia Batista Silva PaivaFlávia Caló de Aquino Xavier
Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2024)
These findings indicate the modulation of cholesterol as a possible mechanism underlying the regulation of these molecules and activation of epithelial-mesenchymal transition in oral squamous cell carcinoma.
Keyphrases
  • epithelial mesenchymal transition
  • low density lipoprotein
  • stem cells
  • transforming growth factor
  • bone marrow