Nucleophilic 1,1-Difluoroethylation with Fluorinated Phosphonium Salt.

Zuyong DengCan LiuXian-Liang ZengJin-Hong LinJi-Chang Xiao

Published in: The Journal of organic chemistry (2016)

The fluorinated phosphonium salt (Ph3P+CF2CH3 BF4-) was shown to act as a nucleophilic 1,1-difluoroethylation agent to enable difluoroethylation of aldehydes and imines.

Keyphrases

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