Reversibility of myocardial metabolism and remodelling in morbidly obese patients 6 months after bariatric surgery.

Jarna Christina HannukainenRiikka LautamäkiJussi PärkkäMarjatta StrandbergVirva SaunavaaraSaija HurmeMinna SoinioPrince DadsonKirsi A VirtanenTove GrönroosSarita ForsbackPaulina SalminenPatricia IozzoPirjo Nuutila

Published in: Diabetes, obesity & metabolism (2018)

In the present study, obesity and age, rather than myocardial substrate uptake, were the causes of cardiac remodelling in morbidly obese patients with or without T2D. Cardiac remodelling and impaired myocardial substrate metabolism are reversible after surgically induced weight loss and amelioration of T2D.

Keyphrases

obese patients
bariatric surgery
weight loss
left ventricular
roux en y gastric bypass
gastric bypass
heart failure
high glucose
type diabetes
metabolic syndrome
weight gain
insulin resistance
glycemic control
endothelial cells
oxidative stress
high fat diet induced
adipose tissue
body mass index
stress induced