Cannabidiol has a unique effect on global brain activity: a pharmacological, functional MRI study in awake mice.
Aymen H SadakaAna G OzunaRichard J OrtizPraveen KulkarniClare T JohnsonHeather B BradshawBruce S CushingAi-Ling LiAndrea G HohmannCraig F FerrisPublished in: Journal of translational medicine (2021)
The CBD-induced decrease in ARAS activity is consistent with an emerging literature suggesting that CBD reduces autonomic arousal under conditions of emotional and physical stress.