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Incidental findings on brain imaging and blood tests: results from the first phase of Insight 46, a prospective observational substudy of the 1946 British birth cohort.

Sarah E KeussThomas D ParkerChristopher A LaneChandrashekar HoskoteSachit ShahDavid M CashAshvini KeshavanSarah M BuchananHeidi Murray-SmithAndrew WongSarah-Naomi JamesKirsty LuJessica CollinsDaniel G BeasleyIan B MaloneDavid L ThomasAnna BarnesMarcus RichardsNick FoxJonathan M Schott
Published in: BMJ open (2019)
In older adults, aged 69-71 years, potentially serious brain MRI findings were detected in around 5% of participants, and clinical blood test abnormalities were present in around one third of participants. Knowledge of the expected prevalence of incidental findings in the general population at this age is useful in both research and clinical settings.
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