A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease.

Signe Holm NielsenDaniel Guldager Kring RasmussenSusanne BrixAnthony FentonMark JeskyCharles J FerroMorten KarsdalFederica GenovesePaul Cockwell

Published in: PloS one (2018)

LG1M, a marker of basement membrane remodeling, is increased in serum and urine of patients with CKD and levels are associated with one-year disease progression, development of ESRD, and mortality.

Keyphrases

cardiovascular events
chronic kidney disease
risk factors
end stage renal disease
bone mineral density
cardiovascular disease
body composition