A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease.
Signe Holm NielsenDaniel Guldager Kring RasmussenSusanne BrixAnthony FentonMark JeskyCharles J FerroMorten KarsdalFederica GenovesePaul CockwellPublished in: PloS one (2018)
LG1M, a marker of basement membrane remodeling, is increased in serum and urine of patients with CKD and levels are associated with one-year disease progression, development of ESRD, and mortality.