FOXA1-induced LINC00621 promotes lung adenocarcinoma progression via activating the TGF-β signaling pathway.

Jingjing WeiHaiyang Yu Tan LiuZiming WangChuandong LangYue-Yin Pan

Published in: Thoracic cancer (2023)

This study uncovered that FOXA1-induced LINC00621 promotes LUAD progression via the miR-34a-5p/TGFBR1/TGF-β axis, and is one novel therapeutic target that may be used in LUAD treatment.

Keyphrases

signaling pathway
high glucose
long non coding rna
cell proliferation
transforming growth factor
diabetic rats
long noncoding rna
pi k akt
epithelial mesenchymal transition
endothelial cells
oxidative stress