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Altered m6A RNA methylation governs denervation-induced muscle atrophy by regulating ubiquitin proteasome pathway.

Junjie SunHai ZhouZehao ChenHan ZhangYanzhe CaoXinlei YaoXin ChenBoya LiuZihui GaoYuntian ShenLei QiHualin Sun
Published in: Journal of translational medicine (2023)
This study indicated that decrease in m6A RNA methylation was a new symptom of denervation-induced muscle atrophy, and confirmed that targeting m6A alleviated denervation-induced muscle atrophy.
Keyphrases
  • high glucose
  • diabetic rats
  • skeletal muscle
  • dna methylation
  • genome wide
  • oxidative stress
  • endothelial cells
  • cancer therapy