Enantioselective S-H Insertion Reactions of α-Carbonyl Sulfoxonium Ylides.
Patrícia B MomoAlexandria N LeveilleElliot H E FarrarMatthew N GraysonAnita E MattsonAntonio Carlos Bender BurtolosoPublished in: Angewandte Chemie (International ed. in English) (2020)
The first example of enantioselective S-H insertion reactions of sulfoxonium ylides is reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to 95 % ee) and yields (up to 97 %) are achieved for 31 examples in S-H insertion reactions of aryl thiols and α-carbonyl sulfoxonium ylides.
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