Ex vivo effects of insulin on the structural integrity of equine digital lamellae.

Cole B SandowL A FuglerB LeiseL RiggsW T MonroeN TotaroJ BelknapS Eades

Published in: Equine veterinary journal (2018)

Insulin weakens the structural integrity of equine lamellar explants and an ex vivo model for evaluation of hyperinsulinaemia-induced lamellar failure was established. The summary is available in Spanish - see Supporting Information.

Keyphrases

type diabetes
glycemic control
high glucose
diabetic rats
drug induced
endothelial cells
oxidative stress
metabolic syndrome
stress induced