Metformin-sensitized NSCLC cells to osimertinib via AMPK-dependent autophagy inhibition.

Hengyi ChenCaiyu LinConghua LuYubo WangRui HanLi LiShuai HaoYong-Hong Pan

Published in: The clinical respiratory journal (2019)

Metformin inhibited autophagy and enhanced osimertinib sensitivity via inducing AMPK activation in a time-dependent manner.

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