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Wild type p53 function in p53Y220C mutant harboring cells by treatment with Ashwagandha derived anticancer withanolides: bioinformatics and experimental evidence.

Durai SundarYue YuShashank P KatiyarJayarani F PutriJaspreet Kaur DhanjalJia WangAnissa Nofita SariEvangelos KolettasSunil C KaulRenu Wadhwa
Published in: Journal of experimental & clinical cancer research : CR (2019)
The study suggested that withanolides may serve as highly potent anticancer compounds for treatment of cancers harboring a p53Y220C mutation.
Keyphrases
  • wild type
  • induced apoptosis
  • oxidative stress
  • combination therapy
  • cell proliferation