Hypoglycaemia and rebound hyperglycaemia increase left ventricular systolic function in patients with type 1 diabetes.
Christine R AndreasenAndreas AndersenPer G HagelqvistJulius V LauritsenPeter Godsk JørgensenSusanne EngbergJens FaberBolette HartmannUlrik Pedersen-BjergaardFilip K Krag KnopTina VilsbøllPublished in: Diabetes, obesity & metabolism (2022)
Hypoglycaemia, recent hypoglycaemia, and overcorrection of hypoglycaemia to rebound hyperglycaemia increased LV systolic function in type 1 diabetes and may imply consideration of plasma glucose when evaluating LV function in patients with type 1 diabetes. An increase in LV systolic function may cause increased strain on the heart and partly explain the link between hypoglycaemia, high glycaemic variability and cardiovascular disease.