Influence of cirrhosis on outcomes of patients with advanced intrahepatic cholangiocarcinoma receiving chemotherapy.

Constance d'AbrigeonMairéad Geraldine McNamaraSamuel Le SourdAngela LamarcaAstrid LièvreHéloïse BourienAlexandre PeinoitThomas UguenRichard A HubnerJuan W Valle Julien Edeline

Published in: British journal of cancer (2023)

Cirrhosis was relatively common in patients with advanced iCC and was associated with increased chemotherapy-induced toxicity and shorter OS. Formal assessment and consideration of cirrhosis in therapeutic management is recommended.

Keyphrases

chemotherapy induced
locally advanced
metabolic syndrome
radiation therapy
glycemic control