Characterization of Typhoid Intestinal Perforation in Africa: Results From the Severe Typhoid Fever Surveillance in Africa Program.
Megan BirkholdShrimati DattaGi Deok PakJustin ImOlakayode O OgundoyinDare I OlulanaTaiwo A LawalOludolapo O AfuwapeAderemi KehindeMarie-France PhobaGaëlle NkojiAbraham AseffaMekonnen TeferiBiruk YeshitelaOluwafemi PopoolaMichael OwusuLady Rosny Wandji NanaEnoch G CakpoMoussa OuedraogoEdgar OuangreIsso OuedraogoAnne-Sophie HeroesJan JacobsOndari D MogeniAndrea HaselbeckLeah SukriKathleen M NeuzilOctavie Lunguya MetilaEllis Owusu-DaboYaw Adu-SarkodieAbdramane Soura BassiahiRaphaël RakotozandrindrainyIruka N OkekeRaphaël M ZellwegerFlorian MarksPublished in: Open forum infectious diseases (2023)
Typhi culture positivity rates, as well as a lack of blood and tissue culture capability in many regions where typhoid remains endemic, significantly underestimate the true burden of typhoid fever. The occurrence of TIP may indicate underlying typhoid burden, particularly in countries with limited culture capability.