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Trends and Differences in Status Epilepticus Treatment of Children and Adults Over 10 Years: A Comparative Study of Medical Records (2012-2021) from a University Hospital in Germany.

Leonore PurwienSusanne Schubert-BastMatthias KieslichMichael W RonellenfitschMichael MerkerMarcus CzabankaLaurent Maximilian WillemsFelix RosenowAdam Strzelczyk
Published in: CNS drugs (2023)
Midazolam has become the preferred benzodiazepine in pre- and in-hospital settings, both in children and adults. The same applies to the increased use of levetiracetam and lacosamide over time in children and adults, while phenobarbital, phenytoin, and valproate use decreased. Continuous midazolam infusion and propofol remain the most frequently used anesthetic drugs. Mortality and outcome remain stable despite changes in medication patterns.
Keyphrases
  • young adults
  • healthcare
  • low dose
  • type diabetes
  • risk factors
  • cardiovascular events
  • drug induced
  • replacement therapy