Hard X-ray imaging and tomography at the Biomedical Imaging and Therapy beamlines of Canadian Light Source.
Sergey GasilovMark Adam WebbArash PanahifarNing ZhuOmar MarinosToby BondDavid M L CooperDean ChapmanPublished in: Journal of synchrotron radiation (2024)
The Biomedical Imaging and Therapy facility of the Canadian Light Source comprises two beamlines, which together cover a wide X-ray energy range from 13 keV up to 140 keV. The beamlines were designed with a focus on synchrotron applications in preclinical imaging and veterinary science as well as microbeam radiation therapy. While these remain a major part of the activities of both beamlines, a number of recent upgrades have enhanced the versatility and performance of the beamlines, particularly for high-resolution microtomography experiments. As a result, the user community has been quickly expanding to include researchers in advanced materials, batteries, fuel cells, agriculture, and environmental studies. This article summarizes the beam properties, describes the endstations together with the detector pool, and presents several application cases of the various X-ray imaging techniques available to users.
Keyphrases
- high resolution
- radiation therapy
- dual energy
- mass spectrometry
- public health
- mental health
- climate change
- magnetic resonance imaging
- cell proliferation
- induced apoptosis
- oxidative stress
- squamous cell carcinoma
- high speed
- mesenchymal stem cells
- computed tomography
- cell therapy
- cell cycle arrest
- photodynamic therapy
- signaling pathway
- fluorescence imaging
- smoking cessation
- endoplasmic reticulum stress
- human health