The usefulness of nuclear area in the diagnosis of high-grade urothelial carcinoma cells in voided urine cytology.

Kazuma SakumoKenta MorihashiAkihiro NakamuraTakuhisa NukayaMakoto SumitomoMuneo NakamuraTadashi SofueReiji HabaTomoo ItohShingo Kamoshida Hiroyuki Ohsaki

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2023)

Our study indicated that nuclear area is a more important cytomorphological criterion than the N:C ratio for HGUC cell detection. Moreover, extracted data of the top five cells were more valuable than the data of all cells, which can be helpful in the routine practice and future criteria definition in urine cytology.

Keyphrases

induced apoptosis
high grade
cell cycle arrest
endoplasmic reticulum stress
healthcare
primary care
electronic health record
big data
low grade
oxidative stress
stem cells
machine learning
cell therapy
deep learning
quality improvement
data analysis
quantum dots